Cyproheptadine is used for: Treating symptoms of allergic reactions (eg, caused by seasonal allergies, food, blood or plasma). It is also used to treat mild, uncomplicated hives. It may also be used for other conditions as determined by your doctor. Cyproheptadine is an antihistamine. It works by blocking the action of histamine to reduce allergy symptoms. Do NOT use cyproheptadine if:

  • you are allergic to any ingredient in cyproheptadine
  • you are breast-feeding
  • the patient is a newborn baby or premature infant
  • you are elderly and in poor health
  • you have narrow-angle glaucoma; a peptic ulcer; an enlarged prostate; or bladder, stomach, or bowel blockage
  • you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or you have taken an MAOI within the last 14 days
  • Contact your doctor or health care provider right away if any of these apply to you.

Before using cyproheptadine

Some medical conditions may interact with cyproheptadine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of asthma; bladder, stomach, or bowel blockage; glaucoma or increased pressure in the eye; difficulty urinating; prostate problems; kidney problems; overactive thyroid; heart problems; high blood pressure; or seizures Some MEDICINES MAY INTERACT with cyproheptadine. Tell your health care provider if you are taking any other medicines, especially any of the following:
  • MAOIs (eg, phenelzine) because they may increase the risk of cyproheptadine's side effects Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because their effectiveness may be decreased by cyproheptadine

This may not be a complete list of all interactions that may occur. Ask your health care provider if cyproheptadine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.