Terlipressin (trade names BRESSIN by Qualtra Pharma ) is an analogue ofvasopressin used as a vasoactive drug in the management of low blood pressure. It has been found to be effective whennorepinephrine does not help. Indications for use include norepinephrine-resistant septic shock[1] and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.

Why it is prescribed (Indications) :
This medication is an analogue of vasopressin, prescribed for bleeding esophageal varices, septic shock, hepatorenal syndrome and in management of low blood pressure. It regulates the body's retention of water by acting to increase water absorption in the kidney.

When it is not to be taken (Contraindications):
Contraindicated in patients with heart disease, chronic kidney inflammation, pregnancy and hypersensitivity.

Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential

Dosage & When it is to be taken :
Adult: IV- Initial: The recommended dose is 2 mg, then 1 or 2 mg 4-6 hourly until bleeding is controlled, up to 72 hour.

How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein.

Warnings and Precautions :
Caution should be exercised in patients with high blood pressure, asthma, hardening of the arteries, heart disease, liver disease, conditions that may be aggravated by water retention, e.g. heart failure.

Side Effects :
Abdominal cramps, chest pain, abnormal heart rhythm, nausea, headache, transient blanching and increased arterial pressure.

Other Precautions :
Avoid excess dosage.

Storage Conditions :
Store it at controlled room temperature (below 25°C).